HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: MARK2 (Q7KZI7)
Serine/threonine-protein kinase MARK2 (EC 2.7.11.1) (EC 2.7.11.26) (ELKL motif kinase 1) (EMK-1) (MAP/microtubule affinity-regulating kinase 2) (PAR1 homolog) (PAR1 homolog b) (Par-1b) (Par1b)
Gene: MARK2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36398662
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0016328 - lateral plasma membrane GO:0035556 - intracellular signal transduction
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 788
+	Hs
		150862 DVL2_HUMAN (1-736): 0: 547: 100.00		MARK3_HUMAN (3-788): 0: 656: 60.40
+	Hs
		151228 DVL2_HUMAN (1-736): 0: 547: 100.00		MARK1_HUMAN (3-788): 0: 644: 63.22
+	Hs
		876427 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		MARK2_HUMAN (1-788): 0: 790: 100.00
+	Hs
		1183065 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		MARK2_HUMAN (1-788): 0: 790: 100.00
+	Hs
		150970 DVL2_HUMAN (1-736): 0: 547: 100.00		AAPK1_HUMAN (31-560): 4.31e-139: 424: 30.37
+	Hs
		647852 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		MARK3_HUMAN (3-788): 0: 656: 60.40
+	Hs
		647919 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		MARK3_HUMAN (3-788): 0: 656: 60.40
+	Hs
		1200015 RIMS1_HUMAN (92-722): 9.64e-47: 181: 14.15		MARK1_HUMAN (3-788): 0: 644: 63.22
+	Dm
		90530 DLG1_DROME (13-707): 2.23e-52: 198: 14.00		E1JGN0_DROME (3-788): 0: 586: 47.55
+	Hs
		647882 PTN13_HUMAN (97-531): 5.7e-17: 88: 15.40		MARK3_HUMAN (3-788): 0: 656: 60.40
+	Rn
		193532 NEB1_RAT (93-347): 2.47e-43: 171: 16.86		AAPK1_RAT (31-560): 2.85e-141: 429: 30.00