HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: OTUL (Q96BN8)
Ubiquitin thioesterase otulin (EC 3.4.19.12) (Deubiquitinating enzyme otulin) (OTU domain-containing deubiquitinase with linear linkage specificity) (Ubiquitin thioesterase Gumby)
Gene: OTULIN

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	1.00	0.850

Property	Details
Experiments	16189514, 23708998, 37589075
Identification Methods	two hybrid, affinity chromatography technology, two hybrid pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	PDZ~Peptidase_C101
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 352
+	Hs
		883936 SYJ2B_HUMAN (258-341): 2.66e-16: 78.4: 30.68		OTUL_HUMAN (1-352): 0: 630: 100.00