HitPredict

Interactor 1: DVL2 (O14641)
Segment polarity protein dishevelled homolog DVL-2 (Dishevelled-2) (DSH homolog 2)
Gene: DVL2

Interactor 2: LRC4C (Q9HCJ2)
Leucine-rich repeat-containing protein 4C (Netrin-G1 ligand) (NGL-1)
Gene: LRRC4C

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 736 Hs			1 640
+	Mm
		1143410 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		LRC4C_MOUSE (1-640): 6.26e-132: 403: 99.69
+	Mm
		936185 DLG3_MOUSE (80-706): 1.04e-71: 252: 15.33		LRC4C_MOUSE (1-640): 6.26e-132: 403: 99.69
+	Mm
		1207544 DLG2_MOUSE (93-707): 2.89e-70: 248: 12.83		LRC4C_MOUSE (1-640): 6.26e-132: 403: 99.69
+	Mm
		1143441 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		LRRT1_MOUSE (23-384): 2.03e-58: 206: 24.03
+	Mm
		471547 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		LRC4B_MOUSE (1-260): 1.06e-40: 160: 22.18
+	Mm
		1193431 DLG1_MOUSE (94-707): 3.76e-84: 287: 15.74		LRFN2_MOUSE (47-427): 3.04e-29: 125: 28.94
+	Rn
		1115171 DLG1_RAT (94-707): 2.78e-80: 277: 15.12		LRFN2_RAT (47-427): 3.07e-29: 125: 28.94
+	Mm
		1143368 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		LRFN2_MOUSE (47-427): 3.04e-29: 125: 28.94
+	Rn
		677783 DLG4_RAT (108-707): 4.11e-75: 258: 15.53		LRFN2_RAT (47-427): 3.07e-29: 125: 28.94
+	Mm
		1103493 DLG1_MOUSE (94-707): 3.76e-84: 287: 15.74		LRFN1_MOUSE (148-520): 4.46e-19: 93.7: 16.71
+	Rn
		1115172 DLG3_RAT (80-706): 4.53e-72: 253: 15.10		LRFN2_RAT (47-427): 3.07e-29: 125: 28.94
+	Mm
		936183 DLG3_MOUSE (80-706): 1.04e-71: 252: 15.33		LRFN2_MOUSE (47-427): 3.04e-29: 125: 28.94
+	Mm
		1143377 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		LRFN4_MOUSE (176-542): 3.68e-23: 106: 15.36
+	Hs
		876494 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		LGR4_HUMAN (4-296): 8.69e-42: 164: 21.70
+	Mm
		1103492 DLG4_MOUSE (108-707): 2.57e-75: 259: 15.85		LRFN1_MOUSE (148-520): 4.46e-19: 93.7: 16.71
+	Hs
		876523 AFAD_HUMAN (256-701): 1.96e-50: 193: 20.93		LRFN1_HUMAN (148-520): 4.18e-19: 93.7: 16.71
+	Hs
		1020181 PTN13_HUMAN (97-531): 5.7e-17: 88: 15.40		LRFN4_HUMAN (1-202): 8.79e-30: 126: 19.72
+	Hs
		280046 MPDZ_HUMAN (242-350): 1.97e-12: 73.4: 28.18		LRFN4_HUMAN (1-202): 8.79e-30: 126: 19.72
+	Hs
		1020230 PTN13_HUMAN (97-531): 5.7e-17: 88: 15.40		LRFN1_HUMAN (148-520): 4.18e-19: 93.7: 16.71