HitPredict

Interactor 1: CHD2 (O14647)
Chromodomain-helicase-DNA-binding protein 2 (CHD-2) (EC 3.6.4.12) (ATP-dependent helicase CHD2)
Gene: CHD2

Interactor 2: EED (O75530)
Polycomb protein EED (hEED) (Embryonic ectoderm development protein) (WD protein associating with integrin cytoplasmic tails 1) (WAIT-1)
Gene: EED

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24457600
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1828 Hs			1 441
+	Hs
		268053 CHD3_HUMAN (32-1580): 0: 981: 24.29		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		268093 CHD4_HUMAN (48-1562): 0: 967: 25.57		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Mm
		1161077 CHD4_MOUSE (48-1562): 0: 951: 25.36		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		57194 CHD7_MOUSE (7-1712): 0: 942: 22.50		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		151440 CHD1_HUMAN (82-1828): 0: 1027: 55.12		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		151443 CHD1_HUMAN (82-1828): 0: 1027: 55.12		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Hs
		151460 CHD1_HUMAN (82-1828): 0: 1027: 55.12		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97
+	Hs
		1059779 CHD4_HUMAN (48-1562): 0: 967: 25.57		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		1018633 CHD3_HUMAN (32-1580): 0: 981: 24.29		SNR40_HUMAN (298-441): 8.27e-22: 98: 14.29
+	Mm
		1161361 SMCA1_MOUSE (349-1347): 0: 785: 29.54		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Mm
		1265290 SMCA5_MOUSE (350-1362): 0: 785: 28.25		EED_MOUSE (1-441): 2.11e-92: 287: 100.00
+	Hs
		1018714 CHD3_HUMAN (32-1580): 0: 981: 24.29		NLE1_HUMAN (4-124): 2.95e-18: 88.8: 9.09
+	Hs
		229258 SMCA5_HUMAN (354-1362): 0: 782: 28.35		EED_HUMAN (1-441): 2.11e-92: 287: 100.00
+	Hs
		903234 CHD4_HUMAN (48-1562): 0: 967: 25.57		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		197011 CHD3_HUMAN (32-1580): 0: 981: 24.29		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Hs
		1254435 CHD6_HUMAN (6-1570): 0: 918: 23.60		FBXW7_HUMAN (219-439): 1.18e-27: 118: 15.32
+	Hs
		197020 CHD4_HUMAN (48-1562): 0: 967: 25.57		PRP4_HUMAN (337-437): 3.12e-09: 60.7: 16.51
+	Hs
		1309165 CHD8_HUMAN (35-1648): 0: 926: 23.19		TBL1Y_HUMAN (277-439): 5.06e-19: 91.1: 13.33
+	Hs
		903535 CHD8_HUMAN (35-1648): 0: 926: 23.19		WDR5_HUMAN (335-440): 3.22e-14: 75.3: 15.09
+	Hs
		1336307 CHD8_HUMAN (35-1648): 0: 926: 23.19		FBW1B_HUMAN (160-352): 1.57e-12: 71.3: 18.97