HitPredict

Interactor 1: CHD2 (O14647)
Chromodomain-helicase-DNA-binding protein 2 (CHD-2) (EC 3.6.4.12) (ATP-dependent helicase CHD2)
Gene: CHD2

Interactor 2: H4 (P62805)
Histone H4
Gene: H4C1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C, CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1828 Hs			1 103
+	Hs
		917182 CHD3_HUMAN (32-1580): 0: 981: 24.29		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917277 CHD4_HUMAN (48-1562): 0: 967: 25.57		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		918062 CHD7_HUMAN (7-1703): 0: 937: 21.90		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917965 CHD8_HUMAN (35-1648): 0: 926: 23.19		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917635 CHD6_HUMAN (6-1570): 0: 918: 23.60		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		917364 CHD9_HUMAN (5-1575): 0: 888: 23.78		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Hs
		229352 SMCA5_HUMAN (354-1362): 0: 782: 28.35		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sp
		144535 HRP3_SCHPO (55-1559): 0: 797: 33.01		H4_SCHPO (18-103): 4.87e-42: 135: 89.54
+	Sc
		356350 CHD1_YEAST (92-1561): 0: 796: 31.19		H4_YEAST (18-103): 6.13e-41: 132: 90.70
+	Dm
		950383 ISWI_DROME (352-1372): 0: 756: 28.09		H4_DROME (1-103): 4.51e-48: 150: 99.03
+	Hs
		846914 SMCA4_HUMAN (25-1223): 0: 743: 23.78		H4_HUMAN (1-103): 1.38e-48: 151: 100.00
+	Sc
		356774 ISW2_YEAST (483-1010): 5.94e-127: 429: 48.60		H4_YEAST (18-103): 6.13e-41: 132: 90.70