HitPredict

Interactor 1: GOSR2 (O14653)
Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin)
Gene: GOSR2

Interactor 2: BET1L (Q9NYM9)
BET1-like protein (Golgi SNARE with a size of 15 kDa) (GOS-15) (GS15) (Vesicle transport protein GOS15)
Gene: BET1L

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000139 - Golgi membrane GO:0005484 - SNAP receptor activity GO:0005794 - Golgi apparatus GO:0005829 - cytosol GO:0015031 - protein transport and 2 others more... GO:0016020 - membrane GO:0031201 - SNARE complex
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 212 Hs			1 111
+	Rn
		192341 GOSR2_RAT (1-212): 1.8e-63: 197: 91.04		BET1_RAT (2-106): 4.23e-36: 120: 31.43
+	Hs
		151530 GOSR2_HUMAN (1-212): 5.78e-61: 191: 100.00		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		169570 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Hs
		151533 GOSR2_HUMAN (1-212): 5.78e-61: 191: 100.00		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	At
		1276968 VTI12_ARATH (1-210): 7.47e-53: 171: 14.87		SYP61_ARATH (3-107): 3.06e-28: 104: 18.10
+	Hs
		169655 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		BET1_HUMAN (2-106): 3.67e-36: 120: 31.43
+	Mm
		292716 VTI1A_MOUSE (2-211): 6.63e-55: 176: 12.38		STX6_MOUSE (1-91): 2.01e-22: 89.7: 16.48
+	Hs
		235202 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Dm
		1373155 GOSR2_DROME (1-211): 5.02e-53: 171: 41.12		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77
+	Rn
		1144364 VTI1A_RAT (2-211): 8.36e-52: 168: 12.09		STX6_RAT (1-92): 1.14e-22: 90.1: 16.30
+	Hs
		212966 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	Hs
		1137468 VTI1A_HUMAN (2-210): 3.39e-52: 169: 11.96		Q5U8S2_HUMAN (7-83): 2.9e-21: 86.2: 11.69
+	Mm
		1265170 Q91XH6_MOUSE (2-210): 9.41e-50: 163: 14.88		STX6_MOUSE (1-91): 2.01e-22: 89.7: 16.48
+	Hs
		235222 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		STX10_HUMAN (7-91): 6.07e-25: 95.9: 12.94
+	Dm
		1374916 Q9W0N6_DROME (1-212): 7.2e-45: 150: 17.89		Q9VVX6_DROME (29-106): 1.21e-24: 91.6: 30.77
+	Hs
		213046 VTI1B_HUMAN (2-190): 7.6e-44: 148: 14.36		STX6_HUMAN (2-91): 2.24e-21: 86.6: 15.56
+	At
		1351880 VTI11_ARATH (1-191): 2.81e-50: 164: 14.36		SYP51_ARATH (13-108): 5.16e-09: 53.5: 19.59