Interactor 1: TOR1A (O14656)
Torsin-1A (Dystonia 1 protein) (Torsin ATPase-1A) (EC 3.6.4.-) (Torsin family 1 member A)
Gene: TOR1A

Interactor 2: TOIP1 (Q5JTV8)
Torsin-1A-interacting protein 1 (Lamin-associated protein 1B) (LAP1B)
Gene: TOR1AIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.956

The method score is based on:

Property Details
Experiments 25352667, 20861018, 19651773, 23569223, 15767459, 20457914
Identification Methods pull down, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation, molecular sieving
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains LAP1_C~Torsin
Common GO terms GO:0005635 - nuclear envelope
GO:0008092 - cytoskeletal protein binding
GO:0031965 - nuclear membrane
GO:0034504 - protein localization to nucleus
GO:0071763 - nuclear membrane organization
Homologous interactions 4

Homologous interactions

Color coding for hit scores

1 332
Hs

1 583
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024