HitPredict

Interactor 1: TMG2 (O14669)
Transmembrane gamma-carboxyglutamic acid protein 2 (Proline-rich gamma-carboxyglutamic acid protein 2) (Proline-rich Gla protein 2)
Gene: PRRG2

Interactor 2: WWTR1 (Q9GZV5)
WW domain-containing transcription regulator protein 1 (Transcriptional coactivator with PDZ-binding motif)
Gene: WWTR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.46	0.60	0.527

Property	Details
Experiments	23873930
Identification Methods	pull down
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 202 Hs			1 400
+	Hs
		1317815 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		WWTR1_HUMAN (1-400): 5.62e-126: 370: 100.00
+	Hs
		152198 TMG2_HUMAN (1-202): 2.51e-90: 265: 100.00		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		808898 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		152185 TMG1_HUMAN (29-198): 2.3e-54: 174: 31.86		YAP1_HUMAN (14-400): 3.72e-97: 300: 41.13
+	Hs
		1317816 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		1294852 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		1176347 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		HECW1_HUMAN (14-327): 1.21e-53: 194: 14.29
+	Hs
		152192 TMG1_HUMAN (29-198): 2.3e-54: 174: 31.86		WWP1_HUMAN (3-386): 5.05e-64: 222: 13.86
+	Hs
		1136436 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		MAGI3_HUMAN (3-246): 4.83e-43: 162: 19.28
+	Hs
		152190 TMG1_HUMAN (29-198): 2.3e-54: 174: 31.86		ITCH_HUMAN (37-356): 2.6e-60: 211: 14.83
+	Hs
		1300667 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		MAGI1_HUMAN (10-212): 9.04e-40: 153: 15.74
+	Hs
		152188 TMG1_HUMAN (29-198): 2.3e-54: 174: 31.86		HECW1_HUMAN (14-327): 1.21e-53: 194: 14.29
+	Mm
		808369 TMG2_MOUSE (1-202): 6.75e-86: 253: 77.18		NEDD4_MOUSE (129-328): 8.42e-21: 96.6: 10.44
+	Hs
		152200 TMG2_HUMAN (1-202): 2.51e-90: 265: 100.00		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		808257 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		1299621 TMG4_HUMAN (10-195): 1.33e-73: 223: 36.04		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		152184 TMG1_HUMAN (29-198): 2.3e-54: 174: 31.86		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		808258 TMG3_HUMAN (29-202): 4.22e-52: 168: 28.78		NEDD4_HUMAN (109-352): 7.33e-23: 103: 11.00
+	Hs
		152191 TMG1_HUMAN (29-198): 2.3e-54: 174: 31.86		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20
+	Hs
		1299622 TMG3_HUMAN (29-202): 4.22e-52: 168: 28.78		NED4L_HUMAN (164-352): 3.03e-13: 73.5: 13.20