HitPredict

Interactor 1: ADA10 (O14672)
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Gene: ADAM10

Interactor 2: TSN12 (O95859)
Tetraspanin-12 (Tspan-12) (Tetraspan NET-2) (Transmembrane 4 superfamily member 12)
Gene: TSPAN12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	19587294
Identification Methods	anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type	association, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 748 Hs			1 305
+	Mm
		192970 ADA10_MOUSE (1-748): 0: 724: 96.00		TSN7_MOUSE (1-254): 5.21e-62: 198: 22.09
+	Hs
		152271 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN5_HUMAN (7-248): 1.91e-60: 195: 19.39
+	Hs
		152234 ADA10_HUMAN (12-748): 0: 717: 100.00		CD63_HUMAN (1-250): 6.27e-60: 193: 26.19
+	Hs
		152306 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN33_HUMAN (10-274): 2.11e-59: 193: 18.88
+	Hs
		152322 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN17_HUMAN (8-249): 1.7e-59: 193: 18.25
+	Mm
		193016 ADA10_MOUSE (1-748): 0: 724: 96.00		TSN14_MOUSE (11-248): 1.74e-56: 185: 20.08
+	Hs
		152213 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN9_HUMAN (4-250): 2.72e-59: 191: 27.13
+	Hs
		152264 ADA10_HUMAN (12-748): 0: 717: 100.00		CD151_HUMAN (3-253): 5.05e-59: 191: 26.64
+	Hs
		152312 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN14_HUMAN (11-248): 6.46e-57: 186: 20.46
+	Hs
		152270 ADA10_HUMAN (12-748): 0: 717: 100.00		CD81_HUMAN (1-251): 3.61e-56: 183: 23.11
+	Hs
		152257 ADA10_HUMAN (12-748): 0: 717: 100.00		CD82_HUMAN (6-254): 2.12e-54: 179: 21.93
+	Hs
		152251 ADA10_HUMAN (12-748): 0: 717: 100.00		CD9_HUMAN (1-253): 1.9e-51: 171: 22.53
+	Hs
		152215 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN15_HUMAN (10-242): 1.04e-47: 163: 19.12
+	Mm
		100228 ADA10_MOUSE (1-748): 0: 724: 96.00		TSN15_MOUSE (10-242): 8.39e-44: 152: 18.73
+	Hs
		326273 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		TSN12_HUMAN (1-305): 2.88e-104: 308: 100.00
+	Ce
		107469 ADA10_CAEEL (23-740): 0: 546: 36.09		TSP12_CAEEL (7-254): 1.2e-46: 161: 16.67
+	Hs
		101800 F8WC54_HUMAN (35-644): 3.49e-147: 446: 21.18		CD81_HUMAN (1-251): 3.61e-56: 183: 23.11
+	Hs
		602243 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		CD9_HUMAN (1-253): 1.9e-51: 171: 22.53
+	Hs
		326052 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		TSN15_HUMAN (10-242): 1.04e-47: 163: 19.12
+	Hs
		1034719 ADAM9_HUMAN (35-644): 7.75e-145: 446: 21.18		TSN18_HUMAN (5-248): 1.24e-29: 114: 19.84