HitPredict

Interactor 1: ADA10 (O14672)
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Gene: ADAM10

Interactor 2: CD63 (P08962)
CD63 antigen (Granulophysin) (Lysosomal-associated membrane protein 3) (LAMP-3) (Lysosome integral membrane protein 1) (Limp1) (Melanoma-associated antigen ME491) (OMA81H) (Ocular melanoma-associated antigen) (Tetraspanin-30) (Tspan-30) (CD antigen CD63)
Gene: CD63

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	26686862
Identification Methods	anti bait coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0043231 - intracellular membrane-bounded organelle GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 748 Hs			1 238
+	Mm
		192970 ADA10_MOUSE (1-748): 0: 724: 96.00		TSN7_MOUSE (1-238): 2.76e-68: 212: 30.33
+	Hs
		152271 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN5_HUMAN (7-235): 4.96e-63: 199: 25.20
+	Hs
		152322 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN17_HUMAN (8-235): 4.87e-62: 197: 27.67
+	Mm
		193016 ADA10_MOUSE (1-748): 0: 724: 96.00		TSN14_MOUSE (11-235): 2.12e-58: 187: 28.00
+	Hs
		152264 ADA10_HUMAN (12-748): 0: 717: 100.00		CD151_HUMAN (3-232): 2.85e-60: 191: 28.22
+	Hs
		152306 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN33_HUMAN (10-234): 6.51e-59: 189: 29.96
+	Hs
		152312 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN14_HUMAN (11-235): 5.91e-59: 189: 27.60
+	Hs
		152213 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN9_HUMAN (4-233): 2.1e-57: 184: 30.04
+	Hs
		152251 ADA10_HUMAN (12-748): 0: 717: 100.00		CD9_HUMAN (1-238): 1.72e-54: 176: 24.49
+	Hs
		152257 ADA10_HUMAN (12-748): 0: 717: 100.00		CD82_HUMAN (4-234): 1.91e-52: 172: 24.13
+	Hs
		152270 ADA10_HUMAN (12-748): 0: 717: 100.00		CD81_HUMAN (1-234): 5.88e-53: 172: 21.63
+	Mm
		100228 ADA10_MOUSE (1-748): 0: 724: 96.00		TSN15_MOUSE (10-232): 1.49e-48: 163: 25.21
+	Hs
		152332 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN10_HUMAN (6-217): 5.22e-50: 168: 23.08
+	Hs
		152215 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97
+	Hs
		152216 ADA10_HUMAN (12-748): 0: 717: 100.00		TSN12_HUMAN (1-227): 1.12e-46: 158: 26.83
+	Ce
		107469 ADA10_CAEEL (23-740): 0: 546: 36.09		TSP12_CAEEL (7-235): 3.39e-51: 170: 24.35
+	Hs
		101800 F8WC54_HUMAN (35-644): 3.49e-147: 446: 21.18		CD81_HUMAN (1-234): 5.88e-53: 172: 21.63
+	Hs
		602243 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		CD9_HUMAN (1-238): 1.72e-54: 176: 24.49
+	Hs
		326052 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		TSN15_HUMAN (10-232): 1.41e-47: 160: 23.97
+	Hs
		326273 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		TSN12_HUMAN (1-227): 1.12e-46: 158: 26.83