HitPredict

Interactor 1: ADA10 (O14672)
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Gene: ADAM10

Interactor 2: NCF1 (P14598)
Neutrophil cytosol factor 1 (NCF-1) (47 kDa autosomal chronic granulomatous disease protein) (47 kDa neutrophil oxidase factor) (NCF-47K) (Neutrophil NADPH oxidase factor 1) (Nox organizer 2) (Nox-organizing protein 2) (SH3 and PX domain-containing protein 1A) (p47-phox)
Gene: NCF1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036101
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0016020 - membrane GO:0017124 - SH3 domain binding GO:0030425 - dendrite
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 748 Hs			1 390
+	Hs
		152280 ADA10_HUMAN (12-748): 0: 717: 100.00		MYO1E_HUMAN (3-283): 4.56e-53: 191: 15.20
+	Hs
		152249 ADA10_HUMAN (12-748): 0: 717: 100.00		NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16
+	Hs
		152325 ADA10_HUMAN (12-748): 0: 717: 100.00		SH3G3_HUMAN (222-285): 2.65e-18: 87.1: 12.50
+	Hs
		152297 ADA10_HUMAN (12-748): 0: 717: 100.00		SH319_HUMAN (81-282): 8.99e-15: 77.9: 17.83
+	Hs
		152209 ADA10_HUMAN (12-748): 0: 717: 100.00		VINEX_HUMAN (85-388): 1.86e-14: 77: 12.95
+	Hs
		537641 ADAM9_HUMAN (35-644): 7.75e-145: 446: 21.18		NCF1_HUMAN (1-390): 1.2e-102: 310: 100.00
+	Hs
		537623 ADAM8_HUMAN (4-645): 3.67e-135: 421: 19.25		NCF1_HUMAN (1-390): 1.2e-102: 310: 100.00
+	Hs
		537670 ADA19_HUMAN (62-656): 2.19e-116: 375: 19.71		NCF1_HUMAN (1-390): 1.2e-102: 310: 100.00
+	Hs
		537642 ADA15_HUMAN (54-625): 7.02e-117: 374: 20.20		NCF1_HUMAN (1-390): 1.2e-102: 310: 100.00
+	Hs
		1034723 ADAM9_HUMAN (35-644): 7.75e-145: 446: 21.18		SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68
+	Hs
		298977 ADAM9_HUMAN (35-644): 7.75e-145: 446: 21.18		SRBS2_HUMAN (163-283): 1.9e-20: 95.7: 21.15
+	Hs
		557788 ADA19_HUMAN (62-656): 2.19e-116: 375: 19.71		NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16
+	Hs
		557680 ADA15_HUMAN (54-625): 7.02e-117: 374: 20.20		NCK1_HUMAN (130-350): 9.29e-34: 131: 17.16
+	Hs
		1307433 ADA19_HUMAN (62-656): 2.19e-116: 375: 19.71		SH3G2_HUMAN (6-211): 5.16e-32: 125: 10.68
+	Hs
		197624 ADA12_HUMAN (52-661): 5.66e-124: 394: 18.10		ITSN2_HUMAN (8-390): 2.54e-15: 80.2: 11.00
+	Hs
		197604 ADA12_HUMAN (52-661): 5.66e-124: 394: 18.10		SH319_HUMAN (81-282): 8.99e-15: 77.9: 17.83
+	Hs
		298978 ADA15_HUMAN (54-625): 7.02e-117: 374: 20.20		SRBS2_HUMAN (163-283): 1.9e-20: 95.7: 21.15
+	Hs
		197601 ADA12_HUMAN (52-661): 5.66e-124: 394: 18.10		ITSN1_HUMAN (54-227): 2.01e-11: 67.7: 12.16
+	Hs
		197606 ADA12_HUMAN (52-661): 5.66e-124: 394: 18.10		SPD2A_HUMAN (206-381): 1.55e-10: 65.1: 20.00
+	Hs
		1136544 ADA19_HUMAN (62-656): 2.19e-116: 375: 19.71		SPD2A_HUMAN (206-381): 1.55e-10: 65.1: 20.00