Interactor 1: ADA10 (O14672)
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Gene: ADAM10

Interactor 2: MMP14 (P50281)
Matrix metalloproteinase-14 (MMP-14) (EC 3.4.24.80) (MMP-X1) (Membrane-type matrix metalloproteinase 1) (MT-MMP 1) (MTMMP1) (Membrane-type-1 matrix metalloproteinase) (MT1-MMP) (MT1MMP)
Gene: MMP14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.33 0.60 0.445

The method score is based on:

Property Details
Experiments 26686862
Identification Methods anti bait coimmunoprecipitation
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0004175 - endopeptidase activity
GO:0004222 - metalloendopeptidase activity
GO:0005178 - integrin binding
GO:0005634 - nucleus
GO:0005886 - plasma membrane
and 5 others

more...

Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 748
Hs

1 582
+ Hs
+ Hs

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Last updated: 15 Jul 2024