HitPredict

Interactor 1: ADA10 (O14672)
Disintegrin and metalloproteinase domain-containing protein 10 (ADAM 10) (EC 3.4.24.81) (CDw156) (Kuzbanian protein homolog) (Mammalian disintegrin-metalloprotease) (CD antigen CD156c)
Gene: ADAM10

Interactor 2: SNX9 (Q9Y5X1)
Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A)
Gene: SNX9

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	25036101
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0030136 - clathrin-coated vesicle GO:0042803 - protein homodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 748 Hs			1 595
+	Hs
		152313 ADA10_HUMAN (12-748): 0: 717: 100.00		SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73
+	Hs
		152323 ADA10_HUMAN (12-748): 0: 717: 100.00		SNX18_HUMAN (1-519): 3.5e-123: 379: 33.09
+	Hs
		1034745 ADAM9_HUMAN (35-644): 7.75e-145: 446: 21.18		SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00
+	Hs
		944533 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00
+	Hs
		941718 ADAM8_HUMAN (4-645): 3.67e-135: 421: 19.25		SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00
+	Hs
		197626 ADA12_HUMAN (52-661): 5.66e-124: 394: 18.10		SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00
+	Hs
		152211 ADA10_HUMAN (12-748): 0: 717: 100.00		GAS7_HUMAN (2-555): 3.16e-52: 187: 13.69
+	Hs
		1327036 ADA19_HUMAN (62-656): 2.19e-116: 375: 19.71		SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00
+	Hs
		1034782 ADA15_HUMAN (54-625): 7.02e-117: 374: 20.20		SNX9_HUMAN (1-595): 5.31e-180: 523: 100.00
+	Hs
		1300856 ATS1_HUMAN (51-659): 2.38e-154: 475: 15.61		SNX18_HUMAN (1-519): 3.5e-123: 379: 33.09
+	Hs
		1034713 ADAM9_HUMAN (35-644): 7.75e-145: 446: 21.18		SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73
+	Hs
		944513 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73
+	Hs
		941714 ADAM8_HUMAN (4-645): 3.67e-135: 421: 19.25		SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73
+	Hs
		1034718 ADAM9_HUMAN (35-644): 7.75e-145: 446: 21.18		SNX18_HUMAN (1-519): 3.5e-123: 379: 33.09
+	Hs
		944518 ADA17_HUMAN (17-647): 1.73e-136: 424: 27.90		SNX18_HUMAN (1-519): 3.5e-123: 379: 33.09
+	Hs
		197615 ADA12_HUMAN (52-661): 5.66e-124: 394: 18.10		SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73
+	Hs
		941716 ADAM8_HUMAN (4-645): 3.67e-135: 421: 19.25		SNX18_HUMAN (1-519): 3.5e-123: 379: 33.09
+	Hs
		1261046 ADA19_HUMAN (62-656): 2.19e-116: 375: 19.71		SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73
+	Hs
		1034764 ADA15_HUMAN (54-625): 7.02e-117: 374: 20.20		SNX33_HUMAN (1-595): 3.41e-135: 407: 34.73
+	Hs
		1034755 ADA15_HUMAN (54-625): 7.02e-117: 374: 20.20		SNX30_HUMAN (169-592): 2.32e-74: 245: 17.82