Interactor 1: ABCD4 (O14678)
Lysosomal cobalamin transporter ABCD4 (EC 7.6.2.8) (ATP-binding cassette sub-family D member 4) (PMP70-related protein) (P70R) (Peroxisomal membrane protein 1-like) (PXMP1-L) (Peroxisomal membrane protein 69) (PMP69)
Gene: ABCD4

Interactor 2: ABCA2 (Q9BZC7)
ATP-binding cassette sub-family A member 2 (EC 7.6.2.-) (ATP-binding cassette transporter 2) (ATP-binding cassette 2)
Gene: ABCA2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.47 1.00 0.691

The method score is based on:

Property Details
Experiments 33961781
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains ABC_membrane_2~ABC_tran, ABC2_membrane_3~ABC_tran, ABC_tran~ABC_tran
Common GO terms GO:0005524 - ATP binding
GO:0005765 - lysosomal membrane
GO:0016020 - membrane
GO:0016887 - ATP hydrolysis activity
GO:0042626 - ATPase-coupled transmembrane transporter activity
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 606
Hs

1 2435
+ Hs

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Last updated: 15 Jul 2024