HitPredict

Interactor 1: ENC1 (O14682)
Ectoderm-neural cortex protein 1 (ENC-1) (Kelch-like protein 37) (Nuclear matrix protein NRP/B) (p53-induced gene 10 protein)
Gene: ENC1

Interactor 2: HS90B (P08238)
Heat shock protein HSP 90-beta (HSP 90) (Heat shock 84 kDa) (HSP 84) (HSP84) (Heat shock protein family C member 3)
Gene: HSP90AB1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	22939624
Identification Methods	luminescence based mammalian interactome mapping
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0043025 - neuronal cell body
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 589 Hs			1 724
+	Hs
		438515 KLH25_HUMAN (1-589): 3.8e-160: 472: 74.70		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		432251 KLH25_HUMAN (1-589): 3.8e-160: 472: 74.70		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		438266 KLH10_HUMAN (34-585): 3.76e-142: 426: 25.89		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		431957 KLH10_HUMAN (34-585): 3.76e-142: 426: 25.89		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		438356 KLH23_HUMAN (20-575): 8.27e-81: 266: 29.05		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		432063 KLH23_HUMAN (20-575): 8.27e-81: 266: 29.05		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		438222 KLH38_HUMAN (17-579): 1.86e-74: 249: 29.78		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		431911 KLH38_HUMAN (17-579): 1.86e-74: 249: 29.78		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		438555 KLHL1_HUMAN (374-589): 1.47e-54: 199: 23.50		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		432290 KLHL1_HUMAN (374-589): 1.47e-54: 199: 23.50		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		438163 KEAP1_HUMAN (386-589): 1.53e-48: 180: 22.12		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		431841 KEAP1_HUMAN (386-589): 1.53e-48: 180: 22.12		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		438402 KLHL6_HUMAN (448-588): 3.4e-22: 102: 24.50		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		438349 KLH36_HUMAN (271-442): 1.2e-20: 98: 16.58		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		438236 KLH26_HUMAN (367-588): 1.33e-19: 94.5: 13.87		HS90B_HUMAN (1-724): 0: 1086: 100.00
+	Hs
		432115 KLHL6_HUMAN (448-588): 3.4e-22: 102: 24.50		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		432055 KLH36_HUMAN (271-442): 1.2e-20: 98: 16.58		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		431925 KLH26_HUMAN (367-588): 1.33e-19: 94.5: 13.87		HS90A_HUMAN (1-724): 0: 1072: 85.25
+	Hs
		1103502 KLH38_HUMAN (17-579): 1.86e-74: 249: 29.78		Q6PK50_HUMAN (1-350): 0: 618: 99.71
+	Hs
		1162529 KLHL1_HUMAN (374-589): 1.47e-54: 199: 23.50		Q6PK50_HUMAN (1-350): 0: 618: 99.71