HitPredict

Interactor 1: ENC1 (O14682)
Ectoderm-neural cortex protein 1 (ENC-1) (Kelch-like protein 37) (Nuclear matrix protein NRP/B) (p53-induced gene 10 protein)
Gene: ENC1

Interactor 2: KLH25 (Q9H0H3)
Kelch-like protein 25 (Ectoderm-neural cortex protein 2) (ENC-2)
Gene: KLHL25

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.73 1.00 0.855

The method score is based on:

Property Details
Experiments 28514442, 33961781, 30190310
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains BACK~BTB, BTB~BTB, Kelch_1~Kelch_1
Common GO terms GO:0005737 - cytoplasm
GO:0016567 - protein ubiquitination
GO:0031463 - Cul3-RING ubiquitin ligase complex
Homologous interactions 19

Homologous interactions

Color coding for hit scores

1 589
Hs

1 589
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024