Interactor 1: KMT2D (O14686)
Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)
Gene: KMT2D
Interactor 2: EZH2 (Q15910)
Histone-lysine N-methyltransferase EZH2 (EC 2.1.1.356) (ENX-1) (Enhancer of zeste homolog 2) (Lysine N-methyltransferase 6)
Gene: EZH2
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 27634302 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | SET~preSET_CXC, SET~SET |
Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006355 - regulation of DNA-templated transcription GO:0008284 - positive regulation of cell population proliferation GO:0031507 - heterochromatin formation and 1 others more... |
Homologous interactions | 18 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024