HitPredict

Interactor 1: KMT2D (O14686)
Histone-lysine N-methyltransferase 2D (Lysine N-methyltransferase 2D) (EC 2.1.1.364) (ALL1-related protein) (Myeloid/lymphoid or mixed-lineage leukemia protein 2)
Gene: KMT2D

Interactor 2: PAGR1 (Q9BTK6)
PAXIP1-associated glutamate-rich protein 1 (Glutamate-rich coactivator interacting with SRC1) (GAS) (PAXIP1-associated protein 1) (PTIP-associated protein 1)
Gene: PAGR1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.703

Property	Details
Experiments	24981860, 33961781, 23508102, 17178841, 17500065
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0033148 - positive regulation of intracellular estrogen receptor signaling pathway GO:0044666 - MLL3/4 complex GO:0045944 - positive regulation of transcription by RNA polymerase II
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 5537 Hs			1 254
+	Hs
		1312207 KMT2B_HUMAN (79-219): 7.24e-25: 117: 24.31		PAGR1_HUMAN (1-254): 3.46e-131: 372: 100.00
+	Hs
		1243838 KMT2C_HUMAN (223-338): 3.09e-09: 66.3: 40.34		PAGR1_HUMAN (1-254): 3.46e-131: 372: 100.00