HitPredict

Interactor 1: RGPD8 (O14715)
RANBP2-like and GRIP domain-containing protein 8 (Ran-binding protein 2-like 3) (RanBP2-like 3) (RanBP2L3)
Gene: RGPD8

Interactor 2: RCC1 (P18754)
Regulator of chromosome condensation (Cell cycle regulatory protein) (Chromosome condensation protein 1)
Gene: RCC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0031267 - small GTPase binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1765 Hs			1 421
+	Hs
		578469 RGPD5_HUMAN (1-1765): 0: 2148: 99.49		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Hs
		63873 RGPD3_HUMAN (1-1757): 0: 2095: 95.68		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Hs
		483381 RGPD1_HUMAN (26-1760): 0: 2084: 93.83		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Hs
		578395 RBP2_HUMAN (866-1488): 4.76e-37: 155: 21.81		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Hs
		578486 RANB3_HUMAN (936-1518): 1.54e-26: 118: 15.13		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Hs
		578387 RANG_HUMAN (1014-1207): 1.21e-28: 116: 37.37		RCC1_HUMAN (1-421): 5.38e-164: 469: 100.00
+	Hs
		319909 GCC2_HUMAN (1003-1765): 2.46e-65: 248: 26.58		HERC2_HUMAN (15-182): 2.22e-22: 102: 19.88
+	Sc
		601761 YRB1_YEAST (998-1173): 5.83e-39: 146: 43.96		RCC1_YEAST (192-419): 1.22e-30: 124: 18.85
+	Sc
		601760 YRB2_YEAST (888-1165): 2.36e-35: 140: 18.49		RCC1_YEAST (192-419): 1.22e-30: 124: 18.85
+	Sc
		601745 NUP2_YEAST (879-1468): 1.38e-29: 129: 13.46		RCC1_YEAST (192-419): 1.22e-30: 124: 18.85