HitPredict

Interactor 1: APAF (O14727)
Apoptotic protease-activating factor 1 (APAF-1)
Gene: APAF1

Interactor 2: RL1D1 (O76021)
Ribosomal L1 domain-containing protein 1 (CATX-11) (Cellular senescence-inhibited gene protein) (Protein PBK1)
Gene: RSL1D1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	30021884
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0042981 - regulation of apoptotic process
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 1248 Hs			1 490
+	Hs
		281204 WDR5_HUMAN (493-728): 4.38e-37: 145: 16.53		RL1D1_HUMAN (1-490): 1.69e-127: 381: 100.00
+	Hs
		281444 NLE1_HUMAN (488-642): 5.63e-18: 90.8: 15.48		RL1D1_HUMAN (1-490): 1.69e-127: 381: 100.00
+	Hs
		281365 SNR40_HUMAN (698-1027): 2.23e-13: 75.1: 22.75		RL1D1_HUMAN (1-490): 1.69e-127: 381: 100.00
+	Sc
		481121 PWP2_YEAST (419-871): 4.14e-34: 144: 11.59		RL1A_YEAST (29-264): 1.01e-66: 215: 21.34
+	Hs
		903103 WDR5_HUMAN (493-728): 4.38e-37: 145: 16.53		RL10A_HUMAN (28-264): 7.51e-66: 213: 15.83
+	Sc
		630858 NLE1_YEAST (1001-1248): 1.16e-56: 207: 14.97		CIC1_YEAST (31-282): 9.75e-39: 146: 21.53
+	Sc
		635568 PWP2_YEAST (419-871): 4.14e-34: 144: 11.59		RL1D1_YEAST (27-265): 7.86e-40: 146: 22.47
+	Sc
		635573 PWP2_YEAST (419-871): 4.14e-34: 144: 11.59		CIC1_YEAST (31-282): 9.75e-39: 146: 21.53
+	Hs
		922514 RACK1_HUMAN (964-1207): 2.09e-10: 65.5: 25.29		RL10A_HUMAN (28-264): 7.51e-66: 213: 15.83
+	Sc
		733617 UTP12_YEAST (1139-1247): 3.14e-13: 76.5: 14.78		RL1D1_YEAST (27-265): 7.86e-40: 146: 22.47
+	Sc
		754225 UTP12_YEAST (1139-1247): 3.14e-13: 76.5: 14.78		CIC1_YEAST (31-282): 9.75e-39: 146: 21.53
+	Hs
		1264784 SNR40_HUMAN (698-1027): 2.23e-13: 75.1: 22.75		TITIN_HUMAN (238-487): 9.15e-10: 63.6: 14.01