Interactor 1: APAF (O14727)
Apoptotic protease-activating factor 1 (APAF-1)
Gene: APAF1
Interactor 2: CASP9 (P55211)
Caspase-9 (CASP-9) (EC 3.4.22.62) (Apoptotic protease Mch-6) (Apoptotic protease-activating factor 3) (APAF-3) (ICE-like apoptotic protease 6) (ICE-LAP6) [Cleaved into: Caspase-9 subunit p35; Caspase-9 subunit p10]
Gene: CASP9
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.97 | 1.00 | 0.988 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 20829884, 27476169, 27197231, 15262985, 9539746, 9488720, 11242052, 28716524, 16979168, 21060833, 9390557, 11113115, 9878060, 19698783, 10376594, 19337385, 16352606, 19118655, 10206961, 9922454 and 1 others
more... |
| Identification Methods | pull down, affinity chromatography technology, two hybrid, molecular sieving, x-ray crystallography, anti tag coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD, CARD~NB-ARC |
| Common GO terms | GO:0001666 - response to hypoxia GO:0001822 - kidney development GO:0005634 - nucleus GO:0005829 - cytosol GO:0006915 - apoptotic process and 6 others more... |
| Homologous interactions | 5 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
