HitPredict

Interactor 1: APAF (O14727)
Apoptotic protease-activating factor 1 (APAF-1)
Gene: APAF1

Interactor 2: CYC (P99999)
Cytochrome c
Gene: CYCS

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.90	0.803

Property	Details
Experiments	16979168, 9267021, 10206961
Identification Methods	affinity chromatography technology, coimmunoprecipitation, pull down
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Cytochrom_C~WD40
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0008635 - activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c GO:0043293 - apoptosome GO:0097193 - intrinsic apoptotic signaling pathway
Homologous interactions	0