Interactor 1: APAF (O14727)
Apoptotic protease-activating factor 1 (APAF-1)
Gene: APAF1
Interactor 2: NLRP1 (Q9C000)
NACHT, LRR and PYD domains-containing protein 1 (EC 3.4.-.-) (EC 3.6.4.-) (Caspase recruitment domain-containing protein 7) (Death effector filament-forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus (NLRP1-CT); NACHT, LRR and PYD domains-containing protein 1, N-terminus (NLRP1-NT)]
Gene: NLRP1
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.47 | 0.90 | 0.656 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 11113115 |
| Identification Methods | affinity chromatography technology, biochemical |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | CARD~CARD, CARD~NB-ARC |
| Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0006919 - activation of cysteine-type endopeptidase activity involved in apoptotic process and 3 others more... |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
