Interactor 1: RIOK3 (O14730)
Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog)
Gene: RIOK3

Interactor 2: IFIH1 (Q9BYX4)
Interferon-induced helicase C domain-containing protein 1 (EC 3.6.4.13) (Clinically amyopathic dermatomyositis autoantigen 140 kDa) (CADM-140 autoantigen) (Helicase with 2 CARD domains) (Helicard) (Interferon-induced with helicase C domain protein 1) (Melanoma differentiation-associated protein 5) (MDA-5) (Murabutide down-regulated protein) (RIG-I-like receptor 2) (RLR-2) (RNA helicase-DEAD box protein 116)
Gene: IFIH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.42 0.60 0.506

The method score is based on:

Property Details
Experiments 25865883
Identification Methods anti tag coimmunoprecipitation, two hybrid
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0032728 - positive regulation of interferon-beta production
GO:0045087 - innate immune response
GO:0051607 - defense response to virus
and 1 others

more...

Homologous interactions 8

Homologous interactions

Color coding for hit scores

1 519
Hs

1 1025
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Last updated: 15 Jul 2024