HitPredict

Interactor 1: MP2K7 (O14733)
Dual specificity mitogen-activated protein kinase kinase 7 (MAP kinase kinase 7) (MAPKK 7) (EC 2.7.12.2) (JNK-activating kinase 2) (MAPK/ERK kinase 7) (MEK 7) (Stress-activated protein kinase kinase 4) (SAPK kinase 4) (SAPKK-4) (SAPKK4) (c-Jun N-terminal kinase kinase 2) (JNK kinase 2) (JNKK 2)
Gene: MAP2K7

Interactor 2: GA45B (O75293)
Growth arrest and DNA damage-inducible protein GADD45 beta (Myeloid differentiation primary response protein MyD118) (Negative growth regulatory protein MyD118)
Gene: GADD45B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.71 0.55 0.625

The method score is based on:

Property Details
Experiments 14743220, 25314077
Identification Methods affinity chromatography technology, pull down, solid phase assay, circular dichroism, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006915 - apoptotic process
GO:0046330 - positive regulation of JNK cascade
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024