HitPredict

Interactor 1: ANM5 (O14744)
Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]
Gene: PRMT5

Interactor 2: RUXF (P62306)
Small nuclear ribonucleoprotein F (snRNP-F) (Sm protein F) (Sm-F) (SmF)
Gene: SNRPF

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0034709 - methylosome
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 637 Hs			1 86
+	Hs
		153838 ANM5_HUMAN (12-637): 0: 862: 100.00		LSM4_HUMAN (7-80): 5.94e-33: 112: 32.00
+	Hs
		153629 ANM5_HUMAN (12-637): 0: 862: 100.00		LSM6_HUMAN (3-77): 1.23e-30: 104: 45.33
+	Hs
		153836 ANM5_HUMAN (12-637): 0: 862: 100.00		LSM2_HUMAN (9-86): 6.59e-24: 88: 28.40
+	Hs
		153631 ANM5_HUMAN (12-637): 0: 862: 100.00		SMD3_HUMAN (5-76): 4.51e-21: 81.9: 22.22