HitPredict

Interactor 1: ANM5 (O14744)
Protein arginine N-methyltransferase 5 (PRMT5) (EC 2.1.1.320) (72 kDa ICln-binding protein) (Histone-arginine N-methyltransferase PRMT5) (Jak-binding protein 1) (Shk1 kinase-binding protein 1 homolog) (SKB1 homolog) (SKB1Hs) [Cleaved into: Protein arginine N-methyltransferase 5, N-terminally processed]
Gene: PRMT5

Interactor 2: LSM4 (Q9Y4Z0)
U6 snRNA-associated Sm-like protein LSm4 (Glycine-rich protein) (GRP)
Gene: LSM4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27247266, 29395067, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000387 - spliceosomal snRNP assembly GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 637 Hs			1 139
+	Hs
		153836 ANM5_HUMAN (12-637): 0: 862: 100.00		LSM2_HUMAN (1-94): 2.68e-36: 121: 28.42
+	Hs
		153630 ANM5_HUMAN (12-637): 0: 862: 100.00		SMD1_HUMAN (1-94): 4.78e-32: 111: 25.26
+	Hs
		153631 ANM5_HUMAN (12-637): 0: 862: 100.00		SMD3_HUMAN (2-108): 2.51e-28: 102: 30.84
+	Hs
		153627 ANM5_HUMAN (12-637): 0: 862: 100.00		RUXF_HUMAN (3-70): 3.59e-27: 98.2: 33.82