HitPredict

Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: UFO (P30530)
Tyrosine-protein kinase receptor UFO (EC 2.7.10.1) (AXL oncogene)
Gene: AXL

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.41	1.00	0.646

Property	Details
Experiments	35384245
Identification Methods	affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PDZ~fn3
Common GO terms	GO:0015629 - actin cytoskeleton GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 358 Hs			1 894
+	Hs
		674422 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		UFO_HUMAN (1-894): 0: 780: 100.00
+	Hs
		153901 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		EPHB1_HUMAN (2-833): 0: 621: 20.70
+	Hs
		153921 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		EPHA7_HUMAN (2-837): 0: 621: 19.50
+	Hs
		674412 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		UFO_HUMAN (1-894): 0: 780: 100.00
+	Hs
		1049958 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		EPHA7_HUMAN (2-837): 0: 621: 19.50
+	Hs
		1072546 LNX2_HUMAN (4-348): 1.22e-27: 115: 14.33		EPHA7_HUMAN (2-837): 0: 621: 19.50
+	Hs
		665600 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		EPHB2_HUMAN (2-837): 0: 605: 19.58
+	Hs
		872639 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		EPHA4_HUMAN (2-836): 0: 637: 19.40
+	Hs
		872433 DLG1_HUMAN (55-238): 9.08e-13: 71.6: 18.85		EPHA5_HUMAN (2-812): 0: 622: 20.39
+	Hs
		153911 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		FAK1_HUMAN (527-851): 1.72e-56: 213: 36.83
+	Hs
		441501 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		MET_HUMAN (536-799): 3.42e-66: 243: 45.90
+	Hs
		153863 NHRF1_HUMAN (1-358): 2.51e-82: 256: 100.00		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Mm
		555008 DLG4_MOUSE (88-235): 4.07e-14: 75.5: 19.36		MET_MOUSE (536-799): 5.47e-66: 243: 45.90
+	Mm
		710140 DLG4_MOUSE (88-235): 4.07e-14: 75.5: 19.36		FAK1_MOUSE (527-889): 3.59e-57: 215: 34.95
+	Hs
		609282 SNTB1_HUMAN (5-347): 5.96e-41: 152: 16.07		FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29
+	Hs
		507990 SNTB1_HUMAN (5-347): 5.96e-41: 152: 16.07		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		169176 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		MUSK_HUMAN (2-147): 3.72e-14: 79: 11.26
+	Hs
		507995 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		FGFR1_HUMAN (10-149): 2.65e-12: 72.9: 15.69
+	Hs
		435639 SCRIB_HUMAN (7-337): 1.45e-29: 122: 19.83		IGF1R_HUMAN (234-385): 4.65e-12: 72.4: 18.07
+	Hs
		280018 MPDZ_HUMAN (1-187): 6.93e-14: 75.1: 22.45		FGFR3_HUMAN (2-135): 5.06e-15: 81.7: 14.29