HitPredict

Interactor 1: NHRF1 (O14745)
Na(+)/H(+) exchange regulatory cofactor NHE-RF1 (NHERF-1) (Ezrin-radixin-moesin-binding phosphoprotein 50) (EBP50) (Regulatory cofactor of Na(+)/H(+) exchanger) (Sodium-hydrogen exchanger regulatory factor 1) (Solute carrier family 9 isoform A3 regulatory factor 1)
Gene: NHERF1

Interactor 2: RHG17 (Q68EM7)
Rho GTPase-activating protein 17 (Rho-type GTPase-activating protein 17) (RhoGAP interacting with CIP4 homologs protein 1) (RICH-1)
Gene: ARHGAP17

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	0.50	0.565

Property	Details
Experiments	33961781, 11285285
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, filter binding
Interaction Type	physical association, association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 358 Hs			1 881
+	Hs
		1075417 NHRF2_HUMAN (5-358): 2.98e-67: 216: 49.44		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		1075409 NHRF2_HUMAN (5-358): 2.98e-67: 216: 49.44		RHG44_HUMAN (1-754): 4.1e-106: 348: 46.20
+	Hs
		1132905 NHRF3_HUMAN (1-133): 3.86e-21: 96.3: 32.35		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		67911 PDZ1P_HUMAN (142-346): 3.81e-15: 77.8: 19.02		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		1148381 DLG3_HUMAN (92-224): 1.53e-09: 61.6: 15.00		RHG17_HUMAN (1-881): 4.48e-144: 450: 100.00
+	Hs
		856141 NHRF2_HUMAN (5-358): 2.98e-67: 216: 49.44		CHIO_HUMAN (231-442): 5.78e-65: 227: 25.12
+	Mm
		1265174 LNX2_MOUSE (1-348): 7.8e-28: 116: 13.76		SRGP2_MOUSE (13-819): 5.39e-85: 296: 14.65
+	Hs
		253346 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		SRGP2_HUMAN (13-819): 1.69e-82: 289: 14.90
+	Hs
		63080 SNX27_HUMAN (12-91): 4.35e-09: 59.7: 37.63		RHG42_HUMAN (1-719): 2.27e-84: 290: 14.59
+	Hs
		253399 MAGI1_HUMAN (109-354): 6.41e-09: 59.7: 15.94		SRGP2_HUMAN (13-819): 1.69e-82: 289: 14.90
+	Hs
		1020174 PTN13_HUMAN (71-237): 3.87e-12: 69.7: 12.97		RHG29_HUMAN (8-786): 6.57e-78: 278: 13.09
+	Mm
		1131438 DLG4_MOUSE (88-235): 4.07e-14: 75.5: 19.36		ABR_MOUSE (1-412): 1.2e-70: 252: 18.94
+	Hs
		506603 NHRF3_HUMAN (1-133): 3.86e-21: 96.3: 32.35		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54
+	Mm
		1143388 DLG4_MOUSE (88-235): 4.07e-14: 75.5: 19.36		RHG32_MOUSE (250-462): 2.1e-17: 89.7: 29.41
+	Hs
		67905 PDZ1P_HUMAN (142-346): 3.81e-15: 77.8: 19.02		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54
+	Hs
		506645 MAGI1_HUMAN (109-354): 6.41e-09: 59.7: 15.94		BCR_HUMAN (250-408): 2.36e-16: 86.3: 33.54