HitPredict

Interactor 1: OVOL1 (O14753)
Putative transcription factor Ovo-like 1 (hOvo1)
Gene: OVOL1

Interactor 2: SMAD7 (O15105)
Mothers against decapentaplegic homolog 7 (MAD homolog 7) (Mothers against DPP homolog 7) (Mothers against decapentaplegic homolog 8) (MAD homolog 8) (Mothers against DPP homolog 8) (SMAD family member 7) (SMAD 7) (Smad7) (hSMAD7)
Gene: SMAD7

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35484112
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0006357 - regulation of transcription by RNA polymerase II GO:0046872 - metal ion binding
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 267 Hs			1 426
+	Hs
		167387 OVOL2_HUMAN (1-267): 1.46e-71: 222: 52.40		SMAD7_HUMAN (1-426): 1.58e-170: 486: 100.00
+	Hs
		950267 OVOL2_HUMAN (1-267): 1.46e-71: 222: 52.40		SMAD3_HUMAN (81-424): 2.22e-146: 424: 26.72
+	Hs
		1078754 ZN251_HUMAN (3-190): 9.94e-65: 215: 15.39		SMAD1_HUMAN (79-424): 2.02e-145: 423: 24.26
+	Hs
		1078644 OVOL2_HUMAN (1-267): 1.46e-71: 222: 52.40		SMAD2_HUMAN (82-424): 5.2e-138: 404: 24.53
+	Hs
		1078780 ZN510_HUMAN (6-266): 3.51e-47: 168: 13.93		SMAD1_HUMAN (79-424): 2.02e-145: 423: 24.26
+	Hs
		1078700 ZN510_HUMAN (6-266): 3.51e-47: 168: 13.93		SMAD2_HUMAN (82-424): 5.2e-138: 404: 24.53
+	Hs
		950213 ZN329_HUMAN (3-115): 1.17e-36: 137: 10.53		SMAD3_HUMAN (81-424): 2.22e-146: 424: 26.72
+	Hs
		1035574 OVOL2_HUMAN (1-267): 1.46e-71: 222: 52.40		SMAD4_HUMAN (54-259): 3.55e-41: 155: 22.75
+	Hs
		1035638 ZN510_HUMAN (6-266): 3.51e-47: 168: 13.93		SMAD4_HUMAN (54-259): 3.55e-41: 155: 22.75
+	Hs
		312062 ZBT7A_HUMAN (120-234): 5.96e-09: 58.2: 30.17		SMAD4_HUMAN (54-259): 3.55e-41: 155: 22.75