HitPredict

Interactor 1: H17B6 (O14756)
17-beta-hydroxysteroid dehydrogenase type 6 (17-beta-HSD 6) (17-beta-HSD6) (EC 1.1.1.105) (EC 1.1.1.209) (EC 1.1.1.239) (EC 1.1.1.53) (EC 1.1.1.62) (3-alpha->beta-hydroxysteroid epimerase) (3-alpha->beta-HSE) (Oxidative 3-alpha hydroxysteroid dehydrogenase) (Short chain dehydrogenase/reductase family 9C member 6)
Gene: HSD17B6

Interactor 2: AT2B2 (Q01814)
Plasma membrane calcium-transporting ATPase 2 (PMCA2) (EC 7.2.2.10) (Plasma membrane calcium ATPase isoform 2) (Plasma membrane calcium pump isoform 2)
Gene: ATP2B2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 1243
+	Hs
		966871 DHRS9_HUMAN (1-308): 5.98e-90: 272: 45.46		AT2B2_HUMAN (1-1243): 0: 1285: 100.00
+	Hs
		154088 H17B6_HUMAN (1-317): 1.43e-108: 320: 100.00		AT2B3_HUMAN (1-1243): 0: 1209: 80.67
+	Hs
		154084 H17B6_HUMAN (1-317): 1.43e-108: 320: 100.00		AT2B1_HUMAN (1-1243): 0: 1186: 78.86
+	Hs
		966904 DHRS7_HUMAN (6-289): 9.82e-65: 208: 23.47		AT2B2_HUMAN (1-1243): 0: 1285: 100.00
+	Hs
		154085 H17B6_HUMAN (1-317): 1.43e-108: 320: 100.00		AT2B4_HUMAN (1-1243): 0: 1154: 68.56
+	Hs
		534438 DHB1_HUMAN (31-281): 5.46e-57: 188: 27.93		AT2B2_HUMAN (1-1243): 0: 1285: 100.00
+	Hs
		588638 DHB11_HUMAN (22-213): 6.86e-59: 192: 25.50		AT2B1_HUMAN (1-1243): 0: 1186: 78.86
+	Hs
		561628 DHB11_HUMAN (22-213): 6.86e-59: 192: 25.50		AT2A2_HUMAN (53-310): 1.78e-54: 209: 27.68