Interactor 1: CHK1 (O14757)
Serine/threonine-protein kinase Chk1 (EC 2.7.11.1) (CHK1 checkpoint homolog) (Cell cycle checkpoint kinase) (Checkpoint kinase-1)
Gene: CHEK1
Interactor 2: MYPT1 (O14974)
Protein phosphatase 1 regulatory subunit 12A (Myosin phosphatase-targeting subunit 1) (Myosin phosphatase target subunit 1) (Protein phosphatase myosin-binding subunit)
Gene: PPP1R12A
Species: Homo sapiens
Source: biogrid
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.55 | 0.90 | 0.708 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 29262732 |
| Identification Methods | affinity chromatography technology, pull down, enzymatic study |
| Interaction Type | physical association, direct interaction |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Ank_2~Pkinase |
| Common GO terms | GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005813 - centrosome GO:0005829 - cytosol |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
