HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: CBL (P22681)
E3 ubiquitin-protein ligase CBL (EC 2.3.2.27) (Casitas B-lineage lymphoma proto-oncogene) (Proto-oncogene c-Cbl) (RING finger protein 55) (RING-type E3 ubiquitin transferase CBL) (Signal transduction protein CBL)
Gene: CBL

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	28972304, 19932172
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 906
+	Hs
		121443 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		154355 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		CBLB_HUMAN (23-901): 0: 793: 46.65
+	Hs
		584313 TNR1A_HUMAN (46-422): 1.95e-65: 218: 19.72		CBL_HUMAN (1-906): 0: 917: 100.00
+	Hs
		610232 TNR5_HUMAN (44-297): 3.52e-40: 146: 16.79		CBL_HUMAN (1-906): 0: 917: 100.00
+	Mm
		610549 TNR5_MOUSE (44-297): 1.92e-41: 150: 16.92		CBL_MOUSE (1-906): 0: 888: 91.59
+	Mm
		192580 TNR11_MOUSE (42-224): 2.38e-32: 131: 17.62		CBL_MOUSE (1-906): 0: 888: 91.59
+	Hs
		154304 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		MUC1_HUMAN (449-906): 3.82e-14: 79.2: 10.58
+	Hs
		554265 TNR1A_HUMAN (46-422): 1.95e-65: 218: 19.72		MUC1_HUMAN (449-906): 3.82e-14: 79.2: 10.58
+	Mm
		648961 TNR5_MOUSE (44-297): 1.92e-41: 150: 16.92		ASPP1_MOUSE (429-870): 1.7e-09: 63.8: 11.96
+	Hs
		257648 FRAS1_HUMAN (8-330): 8.46e-11: 66.6: 12.47		ANR17_HUMAN (410-903): 9.9e-09: 61.5: 11.51