Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: TNR6 (P25445)
Tumor necrosis factor receptor superfamily member 6 (Apo-1 antigen) (Apoptosis-mediating surface antigen FAS) (FASLG receptor) (CD antigen CD95)
Gene: FAS

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.33 1.00 0.575

The method score is based on:

Property Details
Experiments 15659383
Identification Methods biochemical
Interaction Type association

The annotation score is based on:

Property Details
Interacting Pfam domains Death~Death, TNFR_c6~TNFR_c6
Common GO terms GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0009986 - cell surface
GO:0038023 - signaling receptor activity
GO:0042981 - regulation of apoptotic process
and 2 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 440
Hs

1 335
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024