HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: DDR1 (Q08345)
Epithelial discoidin domain-containing receptor 1 (Epithelial discoidin domain receptor 1) (EC 2.7.10.1) (CD167 antigen-like family member A) (Cell adhesion kinase) (Discoidin receptor tyrosine kinase) (HGK2) (Mammary carcinoma kinase 10) (MCK-10) (Protein-tyrosine kinase 3A) (Protein-tyrosine kinase RTK-6) (TRK E) (Tyrosine kinase DDR) (Tyrosine-protein kinase CAK) (CD antigen CD167a)
Gene: DDR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 913
+	Hs
		154297 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52
+	Hs
		121442 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16
+	Hs
		121441 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		FGFR4_HUMAN (554-910): 8.48e-107: 350: 33.87
+	Hs
		522761 TNR1A_HUMAN (46-422): 1.95e-65: 218: 19.72		SRC_HUMAN (361-912): 1.28e-125: 391: 23.60
+	Hs
		436626 TNR16_HUMAN (53-393): 6.19e-51: 179: 16.30		NTRK2_HUMAN (604-906): 1.75e-104: 345: 43.89
+	Rn
		421812 TNR16_RAT (53-393): 2.11e-50: 177: 16.30		NTRK2_RAT (604-906): 6.67e-105: 345: 43.89
+	Rn
		421808 TNR16_RAT (53-393): 2.11e-50: 177: 16.30		NTRK1_RAT (604-906): 3.59e-104: 343: 42.90
+	Hs
		522788 TNR6_HUMAN (52-184): 2.49e-31: 124: 25.53		SRC_HUMAN (361-912): 1.28e-125: 391: 23.60
+	Hs
		507889 TNR3_HUMAN (46-339): 3.8e-35: 137: 16.57		FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52
+	Hs
		601615 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		FGFR2_HUMAN (583-905): 4.2e-109: 357: 34.05
+	Hs
		608195 EDAR_HUMAN (42-327): 3.58e-34: 134: 12.75		FGFR4_HUMAN (554-910): 8.48e-107: 350: 33.87
+	Mm
		626887 TNR1B_MOUSE (38-303): 2.67e-33: 132: 18.64		NTRK1_MOUSE (604-906): 6.84e-105: 345: 43.23
+	Hs
		433256 TNR6_HUMAN (52-184): 2.49e-31: 124: 25.53		YES_HUMAN (563-907): 1.25e-105: 339: 31.59
+	Hs
		609252 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		FGFR3_HUMAN (551-905): 1.32e-110: 360: 32.16
+	Hs
		507951 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		FGFR1_HUMAN (540-905): 6.78e-109: 356: 32.52
+	Hs
		384118 TNR16_HUMAN (53-393): 6.19e-51: 179: 16.30		NTRK1_HUMAN (607-902): 1.43e-66: 240: 45.27
+	Rn
		421810 TNR16_RAT (53-393): 2.11e-50: 177: 16.30		NTRK3_RAT (607-905): 1.68e-63: 232: 40.41