HitPredict

Interactor 1: TR10B (O14763)
Tumor necrosis factor receptor superfamily member 10B (Death receptor 5) (TNF-related apoptosis-inducing ligand receptor 2) (TRAIL receptor 2) (TRAIL-R2) (CD antigen CD262)
Gene: TNFRSF10B

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	32313199, 23142077
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 440 Hs			1 768
+	Hs
		121482 TR10A_HUMAN (5-440): 4.6e-108: 329: 50.00		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		154361 TR10B_HUMAN (1-440): 4.52e-132: 389: 100.00		CUL1_HUMAN (18-768): 0: 707: 30.57
+	Hs
		632273 TNR6_HUMAN (52-184): 2.49e-31: 124: 25.53		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042961 TNR11_HUMAN (62-223): 1.26e-27: 117: 18.61		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		957538 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041960 FRAS1_HUMAN (8-330): 8.46e-11: 66.6: 12.47		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041681 LAMA3_HUMAN (81-201): 7.52e-10: 63.5: 18.37		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		632274 TNR6_HUMAN (52-184): 2.49e-31: 124: 25.53		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		957539 PGBM_HUMAN (32-267): 4.36e-17: 86.2: 15.53		CUL4A_HUMAN (10-768): 0: 791: 38.32