Interactor 1: GNB5 (O14775)
Guanine nucleotide-binding protein subunit beta-5 (Gbeta5) (Transducin beta chain 5)
Gene: GNB5
Interactor 2: RGS7 (P49802)
Regulator of G-protein signaling 7 (RGS7)
Gene: RGS7
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.94 | 1.00 | 0.973 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10521509, 10339615, 9789084, 26186194, 28514442, 19182865, 10051672, 33961781, 19376773 |
| Identification Methods | pull down, affinity chromatography technology, biochemical, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | DEP~WD40, G-gamma~WD40, RGS~WD40, RGS_DHEX~WD40 |
| Common GO terms | GO:0003924 - GTPase activity GO:0005096 - GTPase activator activity GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007186 - G protein-coupled receptor signaling pathway and 1 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
