HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: K2C8 (P05787)
Keratin, type II cytoskeletal 8 (Cytokeratin-8) (CK-8) (Keratin-8) (K8) (Type-II keratin Kb8)
Gene: KRT8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 642 Hs			1 483
+	Hs
		154914 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		K2C75_HUMAN (2-405): 3.9e-79: 258: 64.04
+	Hs
		965426 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		K22O_HUMAN (63-416): 1.87e-152: 450: 65.73
+	Hs
		154918 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		K2C6B_HUMAN (56-405): 2.25e-66: 225: 70.46
+	Hs
		517751 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		K2C3_HUMAN (63-424): 5.15e-135: 405: 65.95
+	Hs
		580131 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		K2C4_HUMAN (55-420): 5.63e-110: 337: 61.96
+	Hs
		409221 UACA_HUMAN (191-641): 1.51e-30: 130: 13.88		K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00
+	Hs
		943628 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		KRT83_HUMAN (12-418): 1.84e-89: 283: 53.07
+	Hs
		409100 TGO1_HUMAN (195-642): 2.07e-29: 127: 15.45		K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00
+	Hs
		213946 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		KRT86_HUMAN (12-418): 3.09e-87: 277: 53.32
+	Hs
		318807 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		K2C75_HUMAN (2-405): 3.9e-79: 258: 64.04
+	Hs
		531529 DESP_HUMAN (214-616): 3.69e-13: 75.4: 14.63		K2C5_HUMAN (56-405): 9.54e-66: 223: 71.02
+	Hs
		359462 DESP_HUMAN (214-616): 3.69e-13: 75.4: 14.63		K2C6A_HUMAN (56-405): 8.09e-65: 220: 70.74
+	Hs
		408995 DESP_HUMAN (214-616): 3.69e-13: 75.4: 14.63		K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00
+	Hs
		409174 DLG5_HUMAN (179-436): 1.03e-12: 73.7: 10.31		K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00
+	Hs
		380474 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		K2C6B_HUMAN (56-405): 2.25e-66: 225: 70.46
+	Hs
		821657 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		K2C6C_HUMAN (56-405): 2.63e-66: 225: 70.74
+	Hs
		408987 MYH1_HUMAN (264-642): 1.43e-11: 69.9: 10.71		K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00
+	Hs
		531569 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		K2C5_HUMAN (56-405): 9.54e-66: 223: 71.02
+	Hs
		409071 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		K2C8_HUMAN (1-483): 2.44e-63: 215: 100.00
+	Hs
		943672 KT33B_HUMAN (266-567): 4.2e-09: 61.1: 19.17		KRT85_HUMAN (145-469): 2.62e-09: 61.4: 12.65