HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: TXLNA (P40222)
Alpha-taxilin
Gene: TXLNA

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.85	0.60	0.718

Property	Details
Experiments	25416956, 29892012, 34079125, unassigned1654, 31515488
Identification Methods	two hybrid, proximity labelling technology, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 642 Hs			1 546
+	Hs
		154918 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		K2C6B_HUMAN (158-522): 3.39e-46: 172: 16.22
+	Hs
		154914 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		K2C75_HUMAN (158-519): 8.16e-43: 162: 16.62
+	Hs
		155135 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		TXLNG_HUMAN (79-514): 3.51e-39: 152: 58.03
+	Hs
		155131 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		MYO5C_HUMAN (213-508): 1.49e-10: 66.3: 14.74
+	Hs
		154949 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CENPE_HUMAN (180-492): 6.33e-09: 61.1: 22.05
+	Hs
		725086 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYO5A_HUMAN (212-511): 4.98e-37: 149: 19.81
+	Hs
		1268124 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		MYO5A_HUMAN (212-511): 4.98e-37: 149: 19.81
+	Rn
		222476 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKB_RAT (178-470): 4.59e-11: 68: 21.28
+	Rn
		361106 MYH6_RAT (190-583): 3.4e-15: 81.7: 10.63		MYH6_RAT (7-523): 1.87e-15: 82.2: 11.70
+	Rn
		1186812 MRCKB_RAT (266-642): 2.4e-19: 95.2: 10.61		MRCKB_RAT (178-470): 4.59e-11: 68: 21.28
+	Hs
		502901 MYH6_HUMAN (243-632): 9.68e-15: 80.2: 14.50		MYH3_HUMAN (89-531): 1.26e-15: 82.6: 13.53
+	Hs
		502933 MYH4_HUMAN (185-613): 1.92e-14: 79.4: 9.46		MYH3_HUMAN (89-531): 1.26e-15: 82.6: 13.53
+	Mm
		93570 MYH9_MOUSE (183-642): 2.55e-18: 91.8: 11.55		DESP_MOUSE (155-503): 2.31e-10: 65.7: 14.43
+	Hs
		725035 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYO5C_HUMAN (213-508): 1.49e-10: 66.3: 14.74
+	Hs
		148460 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CTRO_HUMAN (53-490): 8.24e-10: 63.8: 13.93
+	Hs
		148466 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		CTRO_HUMAN (53-490): 8.24e-10: 63.8: 13.93
+	Hs
		1268099 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		MYO5C_HUMAN (213-508): 1.49e-10: 66.3: 14.74
+	Hs
		148461 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		CTRO_HUMAN (53-490): 8.24e-10: 63.8: 13.93
+	Hs
		528356 MYH6_HUMAN (243-632): 9.68e-15: 80.2: 14.50		MYH6_HUMAN (1-414): 3.64e-10: 64.9: 10.60
+	Hs
		149126 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		CTRO_HUMAN (53-490): 8.24e-10: 63.8: 13.93