HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: DZIP3 (Q86Y13)
E3 ubiquitin-protein ligase DZIP3 (EC 2.3.2.27) (DAZ-interacting protein 3) (RING-type E3 ubiquitin transferase DZIP3) (RNA-binding ubiquitin ligase of 138 kDa) (hRUL138)
Gene: DZIP3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 1208
+	Hs
		154959 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		DCTN1_HUMAN (639-961): 5.05e-41: 167: 15.84
+	Hs
		155089 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CK5P2_HUMAN (522-912): 1.36e-10: 68.1: 10.02
+	Xl
		1160864 NDC80_XENLA (1-640): 2.5e-66: 231: 56.92		DCTN1_XENLA (599-842): 5.43e-09: 62.9: 12.50
+	Rn
		222472 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKA_RAT (595-1186): 3.4e-42: 171: 12.81
+	Hs
		1137917 MRCKB_HUMAN (258-642): 1.73e-21: 102: 12.78		MRCKA_HUMAN (595-1186): 1.78e-41: 169: 11.88
+	Hs
		1137871 MRCKA_HUMAN (140-627): 3.84e-19: 94.5: 11.42		MRCKA_HUMAN (595-1186): 1.78e-41: 169: 11.88
+	Hs
		1127246 TGO1_HUMAN (195-642): 2.07e-29: 127: 15.45		RNF43_HUMAN (1104-1206): 7.85e-24: 110: 26.79
+	Rn
		222476 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKB_RAT (639-1165): 9.61e-20: 98.1: 10.97
+	Hs
		148460 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Rn
		1186812 MRCKB_RAT (266-642): 2.4e-19: 95.2: 10.61		MRCKB_RAT (639-1165): 9.61e-20: 98.1: 10.97
+	Hs
		148466 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		148461 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Hs
		149126 MY18A_HUMAN (210-628): 6.72e-15: 80.8: 14.45		CTRO_HUMAN (565-1050): 7.17e-22: 105: 10.53
+	Mm
		1257475 MYH9_MOUSE (183-642): 2.55e-18: 91.8: 11.55		SYVN1_MOUSE (1108-1192): 9.12e-15: 80.9: 32.58
+	Hs
		724900 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		SYVN1_HUMAN (1108-1192): 8.82e-15: 80.9: 32.58
+	Rn
		361106 MYH6_RAT (190-583): 3.4e-15: 81.7: 10.63		MYH6_RAT (517-1097): 2.36e-16: 87: 7.87
+	Hs
		724976 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CK5P2_HUMAN (522-912): 1.36e-10: 68.1: 10.02
+	Mm
		93570 DESP_MOUSE (190-642): 1.18e-15: 83.5: 15.27		MYH9_MOUSE (694-1163): 2.23e-12: 74.2: 9.05