HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: LRC49 (Q8IUZ0)
Leucine-rich repeat-containing protein 49 (Centriolar satellite-associated tubulin polyglutamylase complex regulator 2) (Tubulin polyglutamylase complex subunit 4) (PGs4)
Gene: LRRC49

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 686
+	Hs
		155108 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		LRCC1_HUMAN (141-315): 3.16e-43: 169: 30.98
+	Hs
		155028 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		CEP97_HUMAN (24-184): 1.03e-10: 67: 16.13
+	Hs
		232794 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		232778 DESP_HUMAN (214-616): 3.69e-13: 75.4: 14.63		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		232942 DLG5_HUMAN (179-436): 1.03e-12: 73.7: 10.31		PHLP1_HUMAN (2-482): 2.72e-46: 179: 11.34
+	Hs
		1315178 MRCKB_HUMAN (258-642): 1.73e-21: 102: 12.78		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		1137902 MRCKA_HUMAN (140-627): 3.84e-19: 94.5: 11.42		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		724996 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		64615 MYH7B_HUMAN (189-642): 9.19e-10: 64.1: 11.40		LRCC1_HUMAN (141-315): 3.16e-43: 169: 30.98
+	Hs
		728512 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		725235 MYH10_HUMAN (171-636): 1.34e-15: 83.3: 12.84		LGR4_HUMAN (5-300): 3.35e-35: 145: 18.50
+	Hs
		502914 MYH3_HUMAN (193-551): 3.19e-12: 72.1: 7.99		PP1R7_HUMAN (12-192): 4.27e-20: 94.3: 23.37
+	Hs
		551759 DESP_HUMAN (214-616): 3.69e-13: 75.4: 14.63		CNTRL_HUMAN (26-183): 5.88e-09: 62: 17.26
+	Hs
		1192486 DLG5_HUMAN (179-436): 1.03e-12: 73.7: 10.31		CNTRL_HUMAN (26-183): 5.88e-09: 62: 17.26