HitPredict

Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: IFT81 (Q8WYA0)
Intraflagellar transport protein 81 homolog (Carnitine deficiency-associated protein expressed in ventricle 1) (CDV-1)
Gene: IFT81

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	34079125, 26186194, 28514442, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005813 - centrosome
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 642 Hs			1 676
+	Hs
		154959 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		DCTN1_HUMAN (253-630): 1.62e-33: 140: 15.26
+	Hs
		155131 NDC80_HUMAN (1-642): 1.46e-79: 266: 100.00		MYO5C_HUMAN (139-589): 1.82e-12: 73.1: 12.50
+	Rn
		222472 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKA_RAT (153-673): 1.27e-39: 159: 12.67
+	Hs
		1137917 MRCKB_HUMAN (258-642): 1.73e-21: 102: 12.78		MRCKA_HUMAN (153-673): 8.71e-39: 156: 13.04
+	Rn
		222476 MRCKA_RAT (181-627): 1.66e-21: 102: 10.82		MRCKB_RAT (144-665): 2.35e-37: 152: 12.36
+	Hs
		1137871 MRCKA_HUMAN (140-627): 3.84e-19: 94.5: 11.42		MRCKA_HUMAN (153-673): 8.71e-39: 156: 13.04
+	Rn
		1186812 MRCKB_RAT (266-642): 2.4e-19: 95.2: 10.61		MRCKB_RAT (144-665): 2.35e-37: 152: 12.36
+	Mm
		93570 MYH9_MOUSE (183-642): 2.55e-18: 91.8: 11.55		DESP_MOUSE (133-660): 1.75e-30: 130: 15.74
+	Hs
		724895 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH14_HUMAN (131-643): 9.15e-29: 125: 17.52
+	Hs
		725002 UACA_HUMAN (191-641): 1.51e-30: 130: 13.88		MYH9_HUMAN (10-534): 8.2e-15: 80.6: 10.46
+	Hs
		724810 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		ROCK1_HUMAN (107-659): 1.21e-22: 105: 13.39
+	Hs
		148460 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		CTRO_HUMAN (108-651): 5.51e-15: 81.2: 15.41
+	Hs
		724686 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH9_HUMAN (10-534): 8.2e-15: 80.6: 10.46
+	Hs
		148466 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		CTRO_HUMAN (108-651): 5.51e-15: 81.2: 15.41
+	Hs
		724687 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYH10_HUMAN (14-413): 8.88e-13: 74.1: 12.16
+	Hs
		725035 MYH9_HUMAN (181-636): 8.68e-18: 90.2: 9.50		MYO5C_HUMAN (139-589): 1.82e-12: 73.1: 12.50
+	Hs
		725097 MYH11_HUMAN (180-641): 3.92e-16: 84.8: 12.24		MYH10_HUMAN (14-413): 8.88e-13: 74.1: 12.16