Interactor 1: NDC80 (O14777)
Kinetochore protein NDC80 homolog (Highly expressed in cancer protein) (Kinetochore protein Hec1) (HsHec1) (Kinetochore-associated protein 2) (Retinoblastoma-associated protein HEC)
Gene: NDC80

Interactor 2: CENPH (Q9H3R5)
Centromere protein H (CENP-H) (Interphase centromere complex protein 35)
Gene: CENPH

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.85 0.60 0.717

The method score is based on:

Property Details
Experiments 33961781, 15713649, 32296183, 34079125, unassigned1304
Identification Methods affinity chromatography technology, two hybrid, proximity labelling technology, validated two hybrid, two hybrid array, two hybrid prey pooling approach, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0007052 - mitotic spindle organization
and 2 others

more...

Homologous interactions 1

Homologous interactions

Color coding for hit scores

1 642
Hs

1 247
+ Gg

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024