Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: PDGFB (P01127)
Platelet-derived growth factor subunit B (PDGF subunit B) (PDGF-2) (Platelet-derived growth factor B chain) (Platelet-derived growth factor beta polypeptide) (Proto-oncogene c-Sis) (Becaplermin)
Gene: PDGFB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 20577048, 16847823
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005615 - extracellular space
GO:0009611 - response to wounding
GO:0014911 - positive regulation of smooth muscle cell migration
GO:0048008 - platelet-derived growth factor receptor signaling pathway
and 1 others

more...

Homologous interactions 7

Homologous interactions

Color coding for hit scores

1 923
Hs

1 241
+ Mm
+ Hs
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024