HitPredict

Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: TM11B (Q86T26)
Transmembrane protease serine 11B (EC 3.4.21.-) (Airway trypsin-like protease 5)
Gene: TMPRSS11B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 923 Hs			1 416
+	Hs
		234442 NRP2_HUMAN (5-923): 0: 907: 44.01		TMPSD_HUMAN (124-416): 1.41e-102: 318: 31.67
+	Hs
		234451 NRP2_HUMAN (5-923): 0: 907: 44.01		ST14_HUMAN (168-416): 1.32e-96: 309: 36.15
+	Hs
		1198140 DCBD2_HUMAN (142-585): 7.3e-70: 249: 23.58		TM11B_HUMAN (1-416): 0: 516: 100.00
+	Hs
		341377 PCOC1_HUMAN (5-314): 1.01e-82: 275: 28.30		PLMN_HUMAN (108-414): 3.11e-100: 317: 27.76
+	Hs
		884421 NETO2_HUMAN (26-307): 6.93e-71: 245: 20.60		TMPS3_HUMAN (158-414): 6.93e-107: 324: 38.08
+	Hs
		1299196 DCBD2_HUMAN (142-585): 7.3e-70: 249: 23.58		TMPSD_HUMAN (124-416): 1.41e-102: 318: 31.67
+	Hs
		1241181 NETO2_HUMAN (26-307): 6.93e-71: 245: 20.60		ST14_HUMAN (168-416): 1.32e-96: 309: 36.15
+	Hs
		1378154 TLL2_HUMAN (8-264): 5.32e-62: 230: 26.62		ST14_HUMAN (168-416): 1.32e-96: 309: 36.15
+	Hs
		428714 BMP1_HUMAN (8-264): 8.47e-65: 238: 25.48		TRY2_HUMAN (184-414): 1.01e-97: 293: 35.35
+	Hs
		119686 MASP2_HUMAN (4-159): 1.49e-26: 118: 21.38		MASP1_HUMAN (40-416): 8.04e-114: 350: 24.25
+	Hs
		119676 MASP2_HUMAN (4-159): 1.49e-26: 118: 21.38		MASP2_HUMAN (37-414): 5.21e-111: 342: 22.51
+	Hs
		409513 MFGM_HUMAN (428-614): 1.1e-32: 133: 29.02		HEPS_HUMAN (157-415): 4.97e-105: 318: 37.27
+	Hs
		995626 MFGM_HUMAN (428-614): 1.1e-32: 133: 29.02		TMPSD_HUMAN (124-416): 1.41e-102: 318: 31.67
+	Hs
		1316671 PCOC2_HUMAN (11-146): 3.83e-32: 132: 32.37		TMPSD_HUMAN (124-416): 1.41e-102: 318: 31.67
+	Hs
		409570 PCOC2_HUMAN (11-146): 3.83e-32: 132: 32.37		HEPS_HUMAN (157-415): 4.97e-105: 318: 37.27
+	Hs
		995632 MFGM_HUMAN (428-614): 1.1e-32: 133: 29.02		TMPS4_HUMAN (143-413): 4.83e-103: 314: 34.93
+	Hs
		995634 MFGM_HUMAN (428-614): 1.1e-32: 133: 29.02		ST14_HUMAN (168-416): 1.32e-96: 309: 36.15
+	Hs
		1356682 PCOC2_HUMAN (11-146): 3.83e-32: 132: 32.37		ST14_HUMAN (168-416): 1.32e-96: 309: 36.15
+	Hs
		341156 C1R_HUMAN (9-146): 3.23e-25: 114: 25.00		C1R_HUMAN (42-414): 1.48e-104: 326: 21.61