HitPredict

Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: MIRO2 (Q8IXI1)
Mitochondrial Rho GTPase 2 (MIRO-2) (hMiro-2) (EC 3.6.5.-) (Ras homolog gene family member T2)
Gene: RHOT2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34709727
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 923 Hs			1 618
+	Hs
		155399 NRP1_HUMAN (1-923): 0: 1068: 100.00		MIRO1_HUMAN (1-618): 0: 763: 59.65
+	Hs
		155362 NRP1_HUMAN (1-923): 0: 1068: 100.00		RAB35_HUMAN (5-168): 3.51e-76: 242: 24.70
+	Hs
		155316 NRP1_HUMAN (1-923): 0: 1068: 100.00		RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34
+	Hs
		155324 NRP1_HUMAN (1-923): 0: 1068: 100.00		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		155322 NRP1_HUMAN (1-923): 0: 1068: 100.00		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		545497 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RAC2_HUMAN (3-183): 1.38e-79: 251: 27.69
+	Hs
		892490 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RAC3_HUMAN (3-168): 9.6e-79: 249: 27.22
+	Hs
		894216 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		CDC42_HUMAN (3-172): 5.67e-77: 244: 25.54
+	Hs
		951157 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RHOG_HUMAN (3-170): 1.68e-74: 238: 27.47
+	Hs
		925440 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RAC1_HUMAN (3-181): 3.15e-74: 237: 26.43
+	Hs
		914288 DCBD2_HUMAN (142-585): 7.3e-70: 249: 23.58		RB11A_HUMAN (416-572): 8.23e-22: 96.2: 20.37
+	Mm
		804666 TLL1_MOUSE (8-274): 1.86e-65: 240: 27.47		RB11B_MOUSE (416-572): 8.06e-22: 96.2: 20.37
+	Mm
		914513 TLL1_MOUSE (8-274): 1.86e-65: 240: 27.47		RB11A_MOUSE (416-572): 8.23e-22: 96.2: 20.37
+	Hs
		915833 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RHOB_HUMAN (6-168): 4.57e-13: 70.1: 29.38
+	Hs
		900693 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RHOA_HUMAN (6-168): 1.74e-11: 65.5: 28.25
+	Hs
		1237995 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RHOF_HUMAN (2-167): 3.37e-11: 65.1: 26.67
+	Hs
		436405 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25
+	Hs
		120540 DCBD1_HUMAN (426-592): 4.21e-41: 163: 27.68		RHOD_HUMAN (3-167): 1.27e-10: 63.2: 28.89
+	Hs
		894740 DDR2_HUMAN (275-424): 2.24e-20: 99: 36.31		RAB8A_HUMAN (411-594): 7.98e-27: 110: 15.34
+	Hs
		436329 DDR2_HUMAN (275-424): 2.24e-20: 99: 36.31		RHOC_HUMAN (6-168): 3.86e-11: 64.3: 28.25