Interactor 1: NRP1 (O14786)
Neuropilin-1 (Vascular endothelial cell growth factor 165 receptor) (CD antigen CD304)
Gene: NRP1

Interactor 2: PLXA1 (Q9UIW2)
Plexin-A1 (Semaphorin receptor NOV)
Gene: PLXNA1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.76 1.00 0.874

The method score is based on:

Property Details
Experiments 25315821, 11886873, 11239433, 36910328
Identification Methods two hybrid, unspecified method, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CUB~Sema
Common GO terms GO:0002116 - semaphorin receptor complex
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0017154 - semaphorin receptor activity
GO:0021828 - gonadotrophin-releasing hormone neuronal migration to the hypothalamus
and 1 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 923
Hs

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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024