HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: TP4A3 (O75365)
Protein tyrosine phosphatase type IVA 3 (EC 3.1.3.48) (PRL-R) (Protein-tyrosine phosphatase 4a3) (Protein-tyrosine phosphatase of regenerating liver 3) (PRL-3)
Gene: PTP4A3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	17353931
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 897 Hs			1 173
+	Hs
		1273211 TNPO1_HUMAN (2-897): 0: 625: 84.39		DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32
+	Hs
		874473 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30
+	Hs
		178137 IPO8_HUMAN (10-847): 3.45e-88: 304: 14.44		TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30
+	Hs
		879802 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30
+	Hs
		890669 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		312225 IPO7_HUMAN (11-850): 2.74e-78: 277: 13.25		TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30
+	Hs
		312229 IPO7_HUMAN (11-850): 2.74e-78: 277: 13.25		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Hs
		874577 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32
+	Sp
		251578 IMB3_SCHPO (7-838): 4.65e-75: 268: 15.72		FLP1_SCHPO (3-160): 6.58e-39: 140: 21.97
+	Hs
		1060903 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32
+	Hs
		312378 IPO7_HUMAN (11-850): 2.74e-78: 277: 13.25		DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32
+	Hs
		246571 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		MCE1_HUMAN (30-138): 1.05e-09: 58.2: 25.00
+	Hs
		260586 IPO4_HUMAN (23-761): 3.84e-35: 146: 17.15		TP4A3_HUMAN (1-173): 7.13e-57: 177: 100.00
+	Hs
		1167724 IPO4_HUMAN (23-761): 3.84e-35: 146: 17.15		TPTE2_HUMAN (6-168): 1.11e-42: 150: 15.85
+	Hs
		879826 IPO4_HUMAN (23-761): 3.84e-35: 146: 17.15		TPTE_HUMAN (6-168): 3.19e-40: 144: 15.30
+	Hs
		890764 IPO4_HUMAN (23-761): 3.84e-35: 146: 17.15		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86
+	Sc
		687983 IMB3_YEAST (7-612): 1.26e-33: 141: 17.08		CDC14_YEAST (11-169): 1.4e-37: 137: 22.73
+	Hs
		1086075 IPO4_HUMAN (23-761): 3.84e-35: 146: 17.15		CDKN3_HUMAN (27-171): 2.36e-28: 106: 22.29
+	Hs
		1256969 IPO4_HUMAN (23-761): 3.84e-35: 146: 17.15		DUS23_HUMAN (30-161): 2.35e-28: 104: 26.32
+	Hs
		127228 IPO5_HUMAN (20-627): 9.22e-15: 81.2: 10.75		PTEN_HUMAN (5-163): 2.34e-41: 144: 18.86