HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: RANG (P43487)
Ran-specific GTPase-activating protein (Ran-binding protein 1) (RanBP1)
Gene: RANBP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0031267 - small GTPase binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 897 Hs			1 201
+	Hs
		796783 TNPO1_HUMAN (2-897): 0: 625: 84.39		RANG_HUMAN (1-201): 7.64e-63: 195: 100.00
+	Hs
		1273208 TNPO1_HUMAN (2-897): 0: 625: 84.39		RGPD5_HUMAN (1-201): 9.73e-47: 166: 34.31
+	Hs
		834809 TNPO1_HUMAN (2-897): 0: 625: 84.39		RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83
+	Hs
		1273239 TNPO1_HUMAN (2-897): 0: 625: 84.39		NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02
+	Xl
		1137361 Q5U4V0_XENLA (2-897): 0: 614: 83.95		Q6DCU3_XENLA (37-160): 2.07e-24: 100: 23.81
+	Hs
		178127 IPO8_HUMAN (10-847): 3.45e-88: 304: 14.44		RANG_HUMAN (1-201): 7.64e-63: 195: 100.00
+	Hs
		796746 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		RANG_HUMAN (1-201): 7.64e-63: 195: 100.00
+	Sc
		746510 IMB2_YEAST (2-894): 6.74e-101: 337: 30.25		YRB1_YEAST (3-165): 2.48e-40: 137: 50.31
+	Hs
		312202 IPO7_HUMAN (11-850): 2.74e-78: 277: 13.25		RANG_HUMAN (1-201): 7.64e-63: 195: 100.00
+	Hs
		483396 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		RGPD1_HUMAN (1-201): 7.66e-48: 169: 34.80
+	Hs
		152779 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		RGPD8_HUMAN (1-201): 9.54e-47: 166: 34.31
+	Hs
		834746 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		RBP2_HUMAN (4-164): 1.49e-44: 160: 47.83
+	Hs
		874611 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02
+	Hs
		1060923 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		RANB3_HUMAN (10-186): 4.16e-30: 117: 16.75
+	Hs
		1060962 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		NUP50_HUMAN (7-161): 5.41e-27: 108: 21.02
+	Sc
		785008 IMB1_YEAST (12-839): 2.32e-74: 263: 14.56		YRB1_YEAST (3-165): 2.48e-40: 137: 50.31
+	Sc
		691667 IMB1_YEAST (12-839): 2.32e-74: 263: 14.56		NUP2_YEAST (3-163): 8.78e-27: 108: 22.22
+	Hs
		796779 IPO4_HUMAN (23-761): 3.84e-35: 146: 17.15		RANG_HUMAN (1-201): 7.64e-63: 195: 100.00
+	Hs
		127208 IPO5_HUMAN (20-627): 9.22e-15: 81.2: 10.75		RANG_HUMAN (1-201): 7.64e-63: 195: 100.00
+	Sc
		687906 IMB3_YEAST (7-612): 1.26e-33: 141: 17.08		NUP2_YEAST (3-163): 8.78e-27: 108: 22.22