HitPredict

Interactor 1: TNPO2 (O14787)
Transportin-2 (Karyopherin beta-2b)
Gene: TNPO2

Interactor 2: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0006606 - protein import into nucleus GO:0008139 - nuclear localization sequence binding
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 897 Hs			1 1475
+	Hs
		834652 TNPO1_HUMAN (2-897): 0: 625: 84.39		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Xl
		1137359 Q5U4V0_XENLA (2-897): 0: 614: 83.95		NU153_XENLA (15-1466): 1.12e-82: 302: 36.55
+	Hs
		834599 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		NU153_HUMAN (1-1475): 2.98e-176: 568: 100.00
+	Hs
		834809 TNPO1_HUMAN (2-897): 0: 625: 84.39		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		1273208 TNPO1_HUMAN (2-897): 0: 625: 84.39		RGPD5_HUMAN (1136-1440): 7.32e-39: 161: 16.72
+	Hs
		727300 TNPO1_HUMAN (2-897): 0: 625: 84.39		NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13
+	Hs
		1273237 TNPO1_HUMAN (2-897): 0: 625: 84.39		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		155553 TNPO2_HUMAN (1-897): 0: 644: 100.00		NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83
+	Hs
		858024 TNPO1_HUMAN (2-897): 0: 625: 84.39		NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83
+	Tt
		101907 G0SGZ5_CHATD (1-897): 2.97e-145: 455: 35.65		NU145_CHATD (865-1304): 7.3e-09: 62.9: 15.28
+	Hs
		834746 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12
+	Hs
		483396 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		RGPD1_HUMAN (1136-1440): 3.02e-38: 159: 16.07
+	Hs
		152779 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		RGPD8_HUMAN (1136-1440): 1.82e-37: 156: 16.72
+	Sc
		595023 IMB2_YEAST (2-894): 6.74e-101: 337: 30.25		NUP1_YEAST (863-1451): 7.24e-23: 108: 18.05
+	Hs
		727228 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13
+	Hs
		727254 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13
+	Hs
		874608 XPO2_HUMAN (3-896): 5.07e-90: 308: 13.52		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		178286 IPO8_HUMAN (10-847): 3.45e-88: 304: 14.44		ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89
+	Hs
		65042 IMB1_HUMAN (11-871): 1.22e-86: 297: 17.83		P121C_HUMAN (211-1269): 1.45e-20: 101: 9.16
+	Dm
		973547 XPO2_DROME (4-894): 1.14e-86: 299: 12.82		CPN_DROME (300-1089): 2.55e-15: 83.7: 7.46